June 2024
Ampath | ampath.co.za
Introducing OCAPLUS
Ampath is proud to launch the Oncomine™ Comprehensive Assay Plus (OCAPLUS) – the most comprehensive solid tumour genetic profiling currently available in South Africa.
Key Features:
- 500 key cancer genes sequenced
- Includes analysis for:
- Tumour Mutational Burden (TMB)
- Microsatellite Instability (MSI)
- Homologous Recombination Deficiency (HRD)
OCAPLUS uses Ion Torrent Next Generation Sequencing (NGS) technology, allowing simultaneous detection of targetable variants across a wide range of solid tumours.
✅ TMB can also be requested as a stand-alone test.
Why Choose OCAPLUS?
- Offers greater genetic coverage than any previous Ampath panel
- Cost-effective alternative to ordering multiple individual tests
- Enables precision oncology with actionable genomic insights
Comparing Key Solid Tumour Assays at Ampath
✅ OCAPLUS (Oncomine™ Comprehensive Assay Plus)
- Genes sequenced: ~500 (including 49 fusion genes)
- Detects:
- Gene fusions
- Copy number variants
- Genomic instability (LOH/HRD)
- Tumour mutational burden (TMB)
- Microsatellite instability (MSI/MMR)
- Turnaround time: 10–14 working days
- Specimen: Tumour tissue
- Mnemonic:
OCAPLUS - Billing codes: 4763 × 1, 4765 × 24
✅ OPANGS (Oncomine™ Precision Assay – DNA only)
- Genes sequenced: ~50 (including 18 fusion genes)
- Detects gene fusions and CNVs
- Turnaround time: 7 working days
- Specimen: Tumour tissue or liquid biopsy
- Mnemonic:
OPANGS - Billing codes: 4763 × 1, 4765 × 10
✅ EGFRRASSEQ
- Genes sequenced: ~50
- Focused panel for specific mutations
- Turnaround time: 7 working days
- Specimen: Tumour tissue or liquid biopsy
- Mnemonic:
EGFRRASSEQ - Billing codes: 4763 × 1, 4765 × 4
For More Information
📞 Contact the NGS Laboratory:
Tel: 012 678 0645
Email: ngs@ampath.co.za
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