Fast Facts

Fast Facts - Infectious Disease Screening During Pregnancy

Fast Facts
Fast Facts - Infectious Disease Screening During Pregnancy
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PATHCHAT Edition
Published: 2024
Please contact your local Ampath pathologist for more information.

Why is Infectious Disease Screening Important During Pregnancy?

Infections can impact both the mother and baby

  • Certain infections can lead to complications such as:
    • Miscarriage.
    • Preterm birth.
    • Congenital anomalies.
    • Severe neonatal infections.

Basic precautions, routine screening, and vaccinations help protect both mother and child.

📌 Early detection and prevention of infections during pregnancy improve outcomes for both mother and baby.

Available Screening Tests for Infections During Pregnancy

Before Falling Pregnant

  • Rubella antibodies:
    • If rubella antibodies are absent or too low, a rubella vaccine should be administered at least one month before conception.

Screening During Early Pregnancy

  • Urine culture:
    • Screens for bacteria in the urine, which can increase the risk of pyelonephritis and preterm birth.
  • Sexually transmitted infections (STIs):
    • HIV.
    • Syphilis.
    • Hepatitis B virus.
    • Other STIs as indicated.

Screening During Late Pregnancy

  • Vagino-rectal swab at 35–37 weeks:
    • Detects Group B Streptococcus (GBS) colonisation.
    • GBS colonisation can result in neonatal sepsis, a life-threatening condition in newborns.
  • Repeat screening for:
    • HIV, syphilis, hepatitis B virus, and other STIs (if indicated).

📌 Routine screening during different pregnancy stages helps prevent complications and ensures appropriate treatment when needed.

Recommended Vaccinations During Pregnancy

Influenza Vaccine

  • Pregnant women are at higher risk of severe complications from influenza.
  • Safe at any stage of pregnancy.
  • Strongly recommended by international guidelines.

Tdap Vaccine (Tetanus, Diphtheria, and Pertussis)

  • Protects newborns from pertussis (whooping cough), which can be life-threatening.
  • Administered between 27–36 weeks of pregnancy.
  • Provides passive immunity to the baby through transplacental antibody transfer.

SARS-CoV-2 (COVID-19) Vaccine

  • Recommended for all pregnant women to reduce the risk of severe illness and complications.

📌 Vaccination during pregnancy helps protect both the mother and baby from severe infections.

How to Stay Healthy During Pregnancy

Safe Sexual Practices

  • Prevention of STIs through safe sex reduces pregnancy complications.

Avoid High-Risk Foods

  • Do not consume:
    • Raw eggs.
    • Undercooked, raw, or processed meat.
    • Unpasteurised milk, cheese, and fruit juice.
    • Raw sprouts and unwashed fresh produce.

Avoid Animal-Associated Infections

  • Avoid handling cat litter to reduce the risk of toxoplasmosis.
  • Avoid petting zoos and contact with farm animals.

📌 Following basic hygiene and food safety practices can prevent many infections during pregnancy.

Contact Information

For more information or to arrange testing, contact:

📌 Screening and vaccination during pregnancy are essential for maternal and newborn health.