Fast Facts

Fast Facts - Liquid-Based Cytology (LBC)

Fast Facts
Fast Facts - Liquid-Based Cytology (LBC)
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PATHCHAT Edition
Published: 2024
Please contact your local Ampath pathologist for more information.

Why Liquid-Based Cytology (LBC) Matters

Cervical Cancer and the Need for Better Screening

  • Cervical cancer is the second most common malignancy in South African women.
  • Despite over 65 years of Pap testing, cervical cancer remains a major public health concern.
  • Advances such as LBC have significantly improved cervical cancer detection and reduced mortality rates.

Benefits of LBC Over Conventional Pap Smears

  • Provides better sample quality.
  • Improves reproducibility, sensitivity, and specificity for detecting cervical cancer lesions.
  • Allows additional cytology, ancillary testing, and digital computer-assisted analysis.

📌 LBC enhances cervical cancer screening by reducing sample contamination and improving accuracy.

What is Liquid-Based Cytology (LBC)?

How LBC Works

  • An improved method of collecting cervical cell samples.
  • Instead of spreading cells on a slide, they are suspended in a fixative liquid.
  • This method removes contaminants such as blood, mucus, and inflammatory cells.

Advantages of LBC Over Conventional Pap Smears

  • Increases accuracy in detecting cervical cancer and precursor lesions.
  • Reduces the need for repeat Pap tests, lowering costs and patient inconvenience.
  • Enables additional tests (HPV subtyping, cytology) using the same sample within 30 days.

📌 LBC produces cleaner, more interpretable samples, reducing false negatives and the need for repeat testing.

LBC Testing Platforms

Current LBC Technologies
ThinPrep®
SurePath®

Why Use These Platforms?

  • Both provide increased accuracy in detecting:
    • Cervical cancer.
    • Atypical cells.
    • Precursor lesions.
  • Samples can be used for primary HPV screening and additional triage tests.

📌 LBC technology improves screening efficiency and offers more flexible testing options.

Why Choose LBC?

Key Benefits
Saves Lives: Early detection of cervical cancer improves outcomes.
Superior Sample Quality: LBC samples are free from contamination.
Flexible Testing: A single sample can be used for multiple tests, including HPV subtyping.
Cost-Effective:

  • LBC test price: R269.60.
  • 20% discount available for upfront payment.

📌 LBC enables a more comprehensive and accurate cervical cancer screening approach.

Contact Information

For more details or to arrange testing, contact:

📌 Switching to LBC ensures better cervical cancer screening with improved accuracy and efficiency.